Patient/caregiver was educated on contraindications for using Aspirin as follows:
- Aspirin and metabolites are mainly excreted in urine by the kidneys. Individuals with renal disease cannot excrete aspirin normally, which allows the metabolites of the medication to stay in blood circulation for longer time, resulting in toxicity and consequent side-effects. Also, aspirin use in high doses, can compromise blood flow to the kidneys, thus significantly increasing the risk for progressive kidney damage and renal failure. Aspirin carries the risk of contributing to exacerbation of renal failure, in individuals with history of the same. So, aspirin use is discouraged in such individuals or used with caution, with periodical monitoring for renal functions and development of any toxic symptoms.
- Individuals with history of breathing disorders, such as, asthma and COPD, secondary to aspirin intake, can sometimes be at increased risk for presentation with exacerbation of SOB and severe debility due to respiratory arrest.
- Aspirin use can inhibit the formation of protective mucus cover on the inner lining of the stomach and thus, can lead to irritation of the stomach lining, gastric upset, and burning sensation of the stomach. This also can lead to reactivation of history of gastric ulcers and/or development of new gastric ulcers. So, aspirin use is discouraged in individuals with history of gastric ulcers.
