Patient/caregiver was educated on contraindications for using Zyloprim as follows:
- Zyloprim is significantly metabolized in the liver and excreted in urine, by the kidneys. If liver function is deficient, metabolism of Zyloprim could be slowed down. Slowing down of the drug metabolism can result in increased risk for compromised therapeutic benefits and toxicity with the medication. Also, Zyloprim carries a risk of liver damage and compromised liver function and so, should be very cautiously used and liver function closely monitored in individuals with history of liver injury.
- Zyloprim is significantly eliminated in urine, by the kidneys. Individuals with renal disease and diminished renal function cannot eliminate Zyloprim from their body normally, which allows the medication to be in the blood stream longer, thus increasing the risk for side-effects and toxicity with the medication. Zyloprim should be very cautiously used and renal function closely monitored in individuals with history of renal damage and compromised kidney function.
- Do not use this medication if you have history of allergy or serious side-effects to Zyloprim intake.
- Zyloprim use is contraindicated in individuals with any history of bone marrow suppression. Zyloprim has potential to induce bone marrow suppression or exacerbate any history of the same, thus resulting in reduced production of red blood cells, white blood cells, and platelets. Zyloprim is administered with extreme caution in individuals with history of severe anemia, opportunistic infections, easy bruising and bleeding.
