Patient was educated on the side effects of using Duragesic as follows:

  1. Feeling of high and addiction
  • Duragesic, in the process of altering the perception of pain in the brain, promotes more dopamine in the brain.
  • Increased dopamine in the brain produces a feeling of high, by interacting with the brain’s reward circuit.
  • This feeling of high, experienced by the individuals on Duragesic use, becomes highly desirable and thus adds the potential for addiction to Duragesic.
  • This makes Duragesic one of the most commonly abused drugs.
  1. Tolerance and addiction
  • Individual using Duragesic at a recommended dose for prolonged time can develop tolerance to the drug and experience blunting of the therapeutic response to Duragesic at that dose.
  • Diminishing therapeutic response prompts an individual to increase the dose of medication intake, to derive the desired effect.
  • This sets the cycle for addiction and abuse.
  1. Withdrawal syndrome
  • Reducing your dosage gradually over a period is the preferred way to quit Duragesic.
  • Sudden withdrawal from Duragesic may induce intense unpleasant sensations, such as, nausea, vomiting, intense muscle aches, sleep disturbances, abdominal cramps, and diarrhea.
  1. Skin rash
  • Duragesic intake can result in mild skin rash and dermatitis.