Patient/caregiver was educated on Glucophage and its mechanism of action as follows:
Gestational diabetes
- Gestational diabetes is a condition of poor blood sugar control that pregnant women develop. Placenta in pregnant women produces certain hormones that block or reduce the action of insulin. Reduced action of insulin hormone in individuals with gestational diabetes leads to poor shifting of glucose in the blood into the cells of body tissues. This leads to poor regulation of blood sugar levels with higher blood sugar numbers and poor nutrition supply to the cells of body tissues. Gestational diabetes can resolve once the pregnancy is over, but it can raise the risk of the individual turning type 2 diabetic later in life.
- Glucophage mainly helps with increasing the sensitivity and decreasing the resistance of body cells for action of insulin. Increased action and utilization of insulin in individuals with gestational diabetes leads to increased uptake of glucose by cells from the blood. Increased glucose uptake from blood contributes to lowered blood sugar levels. Lowered blood sugars reduce demand for more insulin production and thus reduces exposure of body cells to high insulin levels.
Polycystic ovarian syndrome
- Polycystic ovarian syndrome is a hormonal disorder in women of reproductive age group. Women with PCOS can present with one or more features of the conditions, such as, infrequent or prolonged menstrual periods, abnormally increased menstrual bleeding, weight gain/obesity, excess male sex hormone (androgen) levels. The ovaries in women with PCOS may develop numerous small collections of fluid and fail to release eggs at regular timeframe. The exact cause of PCOS is not clear but has a strong association with increased insulin levels in the blood and increased insulin resistance. Increased insulin levels can lead to increased androgen levels, thus contributing to anovulation and infertility in women. Increased androgen levels in women with PCOS can result in cardiovascular complications later in life.
- Glucophage mainly helps with increasing the sensitivity and decreasing the resistance of body cells for action of insulin. Increased action and utilization of insulin in women with PCOS leads to increased insulin consumption and increased uptake of glucose by cells from the blood. Increased glucose uptake from blood contributes to lowered blood sugar levels. Improved blood sugar control can help with preventing excess weight gain in women with PCOS. Lowered blood sugars reduce demand for more insulin production and thus reduces the risk for elevated insulin levels in the body. Increased insulin consumption and reduced blood insulin levels can help reduce androgen production in women with PCOS, which can help with regulating the ovulation cycles and improve fertility.
