Patient was educated on dipeptidyl peptidase 4 inhibitors and their mechanism of action as follows:
- Some individuals with type-2 diabetes are deficient in the secretion of incretins.
- The deficiency in incretin secretion will contribute to reduced insulin secretion in these individuals, which leads to elevated blood sugars.
- Over time, Incretins are naturally degraded by the action of enzyme, dipeptidyl peptidase.
- Inhibition of the enzyme dipeptidyl peptidase, by these medications (Gliptins, in short) allows the incretins to be active for longer period.
- Incretins active for longer time will contribute towards increased insulin secretion, which increases the tissue uptake of glucose and reduces the blood sugar.
- These Gliptins can be used alone or in combination with other medications to manage cases of type-2 diabetes.