Patient/caregiver was educated on contraindications for using Zantac as follows:
- Do not use this medication if you have history of allergy or serious side-effects to Zantac or use of any other medication belonging to the group of H2 blockers, such as, cimetidine and famotidine.
- Zantac is significantly metabolized in the liver. If liver function is deficient, metabolism of Zantac could be slowed down. Slowing down of the drug metabolism can result in increased risk for compromised therapeutic benefits and side-effects with the medication.
- Zantac is significantly eliminated in urine, by the kidneys. Individuals with renal disease and diminished renal function cannot eliminate Zantac from their body normally, which allows the medication to be in the blood stream longer, thus increasing the risk for side-effects and toxicity with the medication.
- Zantac is carefully administered in individuals with compromised liver and renal function, with periodical evaluation of liver and kidney functions.
