Patient was educated on contraindications for using Celecoxib as follows:
- Celecoxib must be avoided or used cautiously in individuals with history of hypertension and heart failure. Reduced renal function, secondary to Celecoxib intake, can contribute towards compromise in filtration of blood, leading to reduced formation of urine and fluid back up in the body. Fluid accumulation in the body can result in edema and weight gain. This backed up fluid can increase the fluid volume and workload on the heart that is already in failure, thus further worsening the cardiac function.
- Celecoxib has the potential to compromise coronary circulation and result in chest pain and myocardial infarction. So, Celecoxib must be avoided or used cautiously in individuals with history of myocardial infarction. Celecoxib must also be avoided during immediate post-surgical period, in individuals who underwent coronary artery bypass grafting (CABG).
- Celecoxib is mainly metabolized by the liver and Celecoxib intake can lead to hepatic injury. Individuals with history of compromised liver function cannot metabolize Celecoxib and this can lead to increased blood levels of Celecoxib for longer duration, leading to toxicity. Celecoxib should be avoided or used with extreme caution in such individuals.
