Patient was educated on contraindications for taking Linagliptin as follows:
- Linagliptin for the significant part is excreted unchanged by the kidneys with very small portion being metabolized in the liver. Individuals with liver and renal dysfunction, cannot metabolize and excrete Linagliptin normally. In such patients with compromised liver and renal functions, Linagliptin can stay active in circulation for longer time and can result in serious hypoglycemic episodes. So, Linagliptin is contraindicated in such individuals.
- Acute pancreatitis is a rare, but serious side effect of using Linagliptin. Patients present with a severe upper abdominal pain, radiating to the back, along with nausea and vomiting. Linagliptin is contraindicated in individuals with history of acute pancreatitis.
- Patients taking Linagliptin rarely can present with an acute gross reduction in urine volume or with absolutely no urine formation. So, Linagliptin is contraindicated in individuals with history of compromised renal function.