Patient/caregiver was educated on contraindications for using omeprazole as follows:
Renal disease
- Omeprazole is significantly eliminated in urine, by the kidneys.
- Individuals with renal disease and diminished renal function cannot eliminate omeprazole from their body normally, which allows the medication to be in the blood stream longer, thus increasing the risk for side-effects and toxicity with the medication.
History of lupus erythematosus
- Omeprazole intake can increase the risk for exacerbation of symptoms of lupus erythematosus in individuals with history of the same.
- Patients can present with diffuse skin rashes. Patients can also present with other constitutional symptoms of fever, headache, pain and inflammation of various joints.
- In individuals with history of lupus, omeprazole use is either discouraged or is administered very carefully with periodical follow-up for any activation of lupus symptoms.
Do not use this medication if you have history of allergy or serious side-effects to omeprazole or use of any other medication belonging to proton pump inhibitors group, such as, lansoprazole and pantoprazole.