Patient/caregiver was instructed upon indications for Pyridoxine supplementation as follows:

  1. Pyridoxine plays a significant role in the synthesis of melatonin, which is the hormone regulating sleep onset and wakefulness. Supplementation with Pyridoxine in deficient states, secondary to the contribution towards melatonin synthesis, can help with relief of symptoms of insomnia, difficulty falling sleep, and regulation of sleep-wake cycle.
  2. Deficiency of Pyridoxine in pregnant women can result in symptoms of morning sickness, delayed fetal growth, and compromised development. Pyridoxine levels must be closely watched during pregnancy and supplements administered in deficient states to help normal fetal growth and development.
  3. Pyridoxine is an essential vitamin needed for synthesis of neurotransmittersand proper functioning of the brain and nerve cells. The levels of neurotransmitters in the brain and nervous system must be closely regulated and balanced, as they are essential in regulating mood and behavior. Deficiency of Pyridoxine can result in compromised development and maturity of nerve and brain cells, compromised synthesis and altered balance of neurotransmitters in the brain, leading to conditions such as peripheral neuropathy, delayed thought processes, cognitive deficits, dementia, anxiety, depression, mania, and psychosis. Supplementation of Pyridoxine in deficient states can contribute towards relief of symptoms with conditions above.