Patient was educated on risk factors for folate deficiency as follows:

  1. Injury to small intestine
  • Folate is normally absorbed in the small intestine.
  • Any injury to small intestine, such as, in individuals with Crohn’s disease or celiac disease, can result in poor folate absorption.
  • Individuals with history of small intestine resection can have reduced site of folate absorption, contributing to compromised folate absorption and deficiency.
  1. Pregnancy
  • In pregnant women, folate helps with normal growth of fetal brain and spinal cord.
  • Deficiency of folate in pregnant women can result in defective growth of brain and spinal cord, resulting in congenital defects.
  • During pregnancy, women can present with folate deficiency, secondary to increased fetal requirements and biological demands of pregnancy.
  1. Medications
  • Chronic use of some antiseizure, antibiotic, and anti-inflammatory medications can interfere and inhibit absorption of folate in small intestine.
  • Reduced absorption of folate can result in folate deficiency.