Patient/caregiver was educated on the side effects of using Imipramine as follows:

Gastrointestinal side-effects                                                                                                            

• Imipramine use can result in common general constitutional symptoms such as, nausea and vomiting. Taking dose of imipramine with a glass of water, after having some food or a snack can help avoid having unpleasant gastrointestinal symptoms with the medication.
• Imipramine can also induce extreme dry mouth and constipation. Sucking on a sugar free hard candy can help with symptomatic relief of dry mouth. Proper hydration measures and compliance with daily fluid intake recommendations can help with relief from constipation. If you experience any further bothersome constipation, report it to your physician for a recommendation on laxative/stool softener use. Observing compliance with fiber intake recommendations in the diet can also help with preventing episodes of constipation with the medication.

Cardiovascular side effects

• Imipramine carries the risk of lowering the blood pressure. Hypotension, secondary to imipramine intake, can lead to episodes of confusion and dizziness, thus increasing the risk for fall and accidents.
• Imipramine also carries the risk of causing and/or aggravating cardiac arrhythmias, leading to severe debility and death. Individuals can present with episodes of chest pain, rapid heart rate, palpitations, dizziness, and shortness of breath.