Patient/caregiver was instructed upon the pathophysiology of seizures as follows:

1. Nerve impulses in the brain are transmitted from one cell to the other as mild electrical impulses.
2. Many factors such as, neurotransmitters in the brain, sodium and glucose concentrations in the blood, bacterial infections, blood and oxygen supply to the brain, and mechanical injury to the brain play a significant role in influencing these nerve impulses in the brain.
3. Some of these factors can act excitatory and some can act inhibitory to the nerve impulses in the brain. Excitatory factors can contribute to increased electrical discharge and nerve impulse transmission in the brain. Inhibitory factors can contribute to reduced electrical discharge and inhibition of nerve impulse transmission in the brain.
4. Excitatory and inhibitory factors influencing the nerve impulse transmission in the brain are usually regulated in a fine balance, in order to avoid excess of either.
5. Disturbance in this fine balance due to any reason, favoring excitatory influence on the nerve impulse conduction in the brain, can result in excess electrical discharge in the brain, contributing to development of seizure activity.