Patient was educated on precautions to be exercised while taking Celebrex as follows:
- Discuss with your doctor regarding any previous allergic responses you experienced with other NSAIDs, such as, Ibuprofen and Celebrex sodium.
- Celebrex must be avoided or used cautiously in individuals with history of exacerbation of SOB with episodes of asthma and growth of nasal polyps with other NSAIDs. Celebrex, in some individuals, is known to evoke similar response. Discuss with your physician about any such history and your safety with Celebrex. Report any exacerbation of shortness of breath to your physician immediately.
- Observe compliance with any regular lab work ordered. As Celebrex is metabolized by the liver and carries the risk for damage to the liver, hepatic function could be periodically monitored, to prevent risk for toxicity. Watch closely to report any symptoms of itching, jaundice with yellowing of skin and sclera, dark urine, altered metabolism with nausea and vomiting, pain in the right upper abdominal quadrant, and fatigue suggesting damage to the liver.
- Celebrex is significantly excreted in the feces and urine. Individuals with history of biliary stasis and compromised renal functions tend to retain the drug in the circulation longer, thus resulting in toxicity. Celebrex should be avoided or used with extreme caution in such individuals. Any symptoms of renal injury and altered kidney function, such as, altered levels of consciousness and reduced urine formation, should be closely watched for and reported to the physician. Discuss with your physician regarding your history of compromised renal function, if any, and your safety with using Celebrex.