Patient/caregiver was instructed upon tamsulosin and mechanism of action of tamsulosin as follows:

  1. The tone of smooth muscle in the prostate gland and the neck of bladder controls the ease of urine flow. This smooth muscle has receptors called alpha-1 receptors, which are acted upon by adrenaline. Adrenaline activity on the alpha – 1 receptors can lead to increased tone of the smooth muscle in the prostate and neck of the urinary bladder, which contributes to obstruction to urine flow.
  2. Also, in some senior citizens, prostate could get enlarged due to various reasons, which can compress the urethra passing through the prostate, thus resulting in symptoms of obstruction to urine flow and benign prostatic hyperplasia.
  3. Tamsulosin belongs to the group of alpha-1 blocker medications, inhibiting the activity of adrenaline on alpha-1 receptors in the smooth muscle of the prostate and neck of the bladder.
  4. This results in reduced tone and relaxation of the smooth muscle in the prostate and neck of the urinary bladder, which helps with smooth and uninterrupted flow of urine.