Patient was educated on serotonin release and reuptake inhibition by Trazodone as follows:
- Serotonin is one among the many neurotransmitters released at one nerve ending, to help transmit the impulse across the synapse (junction between two nerves), to the next nerve.
- Serotonin binds to the receptors on the second nerve and transmits the nerve impulse from the first nerve to the second.
- After the impulse is transmitted to the second nerve, the impulse progresses further, thus propagating the impulse down. But, the receptors on the second nerve relax and release the serotonin back into the synapse, to be taken up back by the first nerve and be released into the synapse again with the next oncoming impulse, propagating from the first to the second nerve.
- Trazodone majorly works by inhibiting the reuptake of serotonin by the nerve endings of the first nerve, at the synapse.
- This helps with increasing the serotonin levels in the synapse and helps with appropriate desired nerve stimulation, thus contributing to reducing depression.
