Patient was educated on contraindications for using biguanides as follows:
- Biguanides are usually not metabolized in the body and for the significant part are excreted unchanged by the kidneys. Individuals with renal disease cannot excrete these medications normally. In such patients with compromised renal function, these medications can stay active in circulation for longer time and can be toxic. So, these medications should be used with caution in individuals with compromised renal function.
- Avoid using biguanides along with alcohol. This can increase the risk of stomach upset with nausea, vomiting, and diarrhea.
- Avoid using biguanides in patients with history of metabolic acidosis with symptoms like rapid breath and heart rate, confusion, and stomach upset with nausea and vomiting.
