Patient was educated on contraindications for taking Sitagliptin as follows:
- Sitagliptin for the significant part is excreted unchanged by the kidneys with very small portion being metabolized in the liver. Individuals with liver and renal dysfunction, cannot metabolize and excrete Sitagliptin normally. In such patients with compromised liver and renal functions, Sitagliptin can stay active in circulation for longer time and can result in serious hypoglycemic episodes. So, Sitagliptin is contraindicated in such individuals.
- Acute pancreatitis is a rare, but serious side effect of using Sitagliptin. Patients present with a severe upper abdominal pain, radiating to the back, along with nausea and vomiting. Sitagliptin is contraindicated in individuals with history of acute pancreatitis.
- Patients taking Sitagliptin rarely can present with an acute gross reduction in urine volume or with absolutely no urine formation. So, Sitagliptin is contraindicated in individuals with history of compromised renal function.
