Patient was educated on contraindications for using Naproxen as follows:
- Patients with history of dyspepsia and heartburn must be cautious about using Naproxen. Discuss with your doctor regarding your history of the same.
- Naproxen must be used cautiously in individuals with history of gastric ulcers, as intake of this medication can lead to increased exposure of the stomach lining to the action of gastric acid, leading to erosion of gastric mucosa and development of gastric ulcers. Using enteric coated Naproxen can help this situation.
- Naproxen must be avoided or used cautiously in individuals with history of compromised renal function. Naproxen inhibits the production of prostaglandins in all the tissues, including the renal. Inhibition of prostaglandin synthesis in the kidneys, result in vasoconstriction and reduced blood flow to the renal tissue. Reduced blood flow to the renal tissue can contribute to further compromise of renal function.
- Naproxen must be avoided or used cautiously in individuals with history of hypertension and heart failure. Reduced renal function, secondary to Naproxen intake, can contribute towards compromise in filtration of blood, leading to reduced formation of urine and fluid back up in the body. Fluid accumulation in the body can result in edema and weight gain. This backed up fluid can increase the fluid volume and workload on the heart that is already in failure, thus further worsening the cardiac function.
