Patient was educated on contraindications for using Marbaxin as follows:
- Marbaxin is mainly metabolized in the liver and the metabolites along with the unmetabolized drug are mainly excreted in the urine. If liver function is deficient, the metabolism of marbaxin can be compromised. If renal function is deficient, the elimination of marbaxin can be compromised. This can lead to increased blood levels of the medication and metabolites for longer periods of time, resulting in increased risk for side-effects and consequent toxicity. So, in individuals with history of compromised liver and/or renal function, marbaxin must be used with caution and possible multiple dose adjustments, periodical monitoring for liver and kidney functions and development of any toxicity symptoms with the medication.
- Marbaxin could interact with a number of other medications and can precipitate serious reactions. If you are being newly started on marbaxin, discuss with your physician regarding all other medications you are currently taking and their safety with marbaxin. Also, if you have been taking marbaxin for long, discuss with your physician regarding your history of marbaxin intake, when you are being started on any new medication.
- Marbaxin use, especially in individuals with seizure history, can occasionally result in deterioration of seizure control and fresh episodes of seizures. Marbaxin must either be avoided for an alternative or used with extra caution in individuals with seizure history, to prevent exacerbation of seizure episodes.
