Therapeutic Uses of Lioresal
- Lioresal is an analog of GABA and works on the same lines, inhibiting the conduction of nerve impulses between the nerves and to the muscles.
- Conduction of nerve impulse to the muscle results in muscle contraction. Upon intake of Lioresal, inhibition of nerve impulse conduction from the spinal cord to the muscle leads to muscle relaxation.
Lioresal can be used in clinical conditions for control of pain and relief of muscle spasticity and tightness as follows:
Cerebral palsy
- Cerebral palsy is a congenital disorder of movement and muscle tone, secondary to abnormal brain development in utero.
- Individuals with cerebral palsy can present with abnormal muscle tone and spasticity. Muscle spasticity can lead to contractures, rigidity, stiffness, and limited range of motion contributing to significant pain, and discomfort.
- Lioresal intake in these individuals can help relieve the spasticity and tightness, relax the muscle, and contribute to relief of pain and stiffness.
Amyotrophic lateral sclerosis (ALS)
- Motor nerves originate in the brain and travelling through the spinal cord, reach the various muscles throughout the body, thus conducting the impulse to the muscles.
- ALS is a condition in which there is progressive degeneration of the motor nerves controlling the activity of the various muscles.
- Progressive degeneration of the motor nerves contributes to altered and compromised impulse conduction.
- Depending on the site of injury and the nerves involves, this change in nerve impulse conduction can result in spasticity or severe tightening of muscles, flaccid weak muscles, and muscle spasms contributing to the pain & discomfort. This can severely compromise the muscle function.
- Lioresal by controlling and relieving the spasticity and tightness, relax the muscle, and contribute to relief of pain and stiffness.
