Patient/caregiver was educated on contraindications for using Orphenadrine as follows:

  1. Do not take orphenadrine, if you ever manifested any allergic responses to intake of orphenadrine. In the event of an allergic response with any of these medications, check with your physician regarding your safety with intake of orphenadrine.
  2. Orphenadrine has some potential for addiction, especially after prolonged use and/or in individuals with history of substance/drug abuse. This makes orphenadrine a risky drug and so, must be avoided for a safer alternative in individuals with history of substance/drug abuse. Discuss with your physician regarding history of substance/drug abuse, if any.
  3. Do not take orphenadrine along with alcohol, opioid pain medications, such as, hydrocodone and codeine, antipsychotic medications, antidepressant medications, anti-seizure medications, muscle relaxants, antihistamines, OTC cough syrups, and any other medications that carry a risk for depression of the central nervous system, resulting in episodes of dizziness and confusion. The individual influence of these medications on central nervous system can get added up, thus leading to confusion, coma, and emergency situations.