Patient/caregiver was educated on contraindications for using Lorzone as follows:

  1. Do not take lorzone, if you ever manifested any allergic responses to intake of lorzone or any other medications belonging to the group of skeletal muscle relaxants, such as, methocarbamol and baclofen. In the event of an allergic response with any of these medications, check with your physician regarding your safety with intake of lorzone.
  2. Lorzone has some potential for addiction, especially after prolonged use and/or in individuals with history of substance/drug abuse. This makes lorzone a risky drug and so, must be avoided for a safer alternative in individuals with history of drug abuse.
  3. Do not take lorzone along with alcohol, opioid pain medications, such as, hydrocodone and codeine, antipsychotic medications, antidepressant medications, anti-seizure medications, muscle relaxants, antihistamines, OTC cough syrups, and any other medications that carry a risk for depression of the central nervous system and the respiratory center, resulting in episodes of dizziness, confusion, difficulty breathing, and respiratory arrest. The individual influence of these medications on respirations and central nervous system can get added up, thus leading to severe respiratory depression, confusion, coma, and can even be fatal.