Patient/caregiver was educated on contraindications for using Carisoma as follows:
- Carisoma is mainly metabolized inside the body by the liver and is excreted out of the body in the urine by the kidneys. If liver is deficient, metabolism of the drug could be compromised, which can result in higher concentrations of the drug in the body for longer periods of time. If kidney function is deficient, elimination of the drug could be compromised, which also can result in higher concentrations of the drug in the body for longer periods of time. Either case can contribute to toxicity and consequent side-effects. So, for individuals with history of severely compromised hepatic and/or renal function, carisoma must be either be avoided for a safer alternative. If carisoma is used for such individuals, extreme caution must be exercised with close monitoring for symptoms of toxicity with carisoma.
- Carisoma use, especially in individuals with seizure history, can occasionally result in deterioration of seizure control and fresh episodes of seizures. So, carisoma could be avoided for a safer alternative in individuals with history of poorly controlled seizures.
- Carisoma could interact with a number of other medications and can precipitate serious reactions. If you are being newly started on carisoma, discuss with your physician regarding all other medications you are currently taking and their safety with carisoma. Also, if you have been taking carisoma for long, discuss with your physician regarding your history of carisoma intake, when you are being started on any new medication.
