Patient/caregiver was educated on the side-effects of using Promethazine as follows:
Hematologic side-effects
- Promethazine intake can also result in bone marrow suppression, resulting in reduced production of blood cells. Low red blood cell production can result in findings of anemia and individuals can present with pallor of skin and mucosa, fatigue, dizziness, shortness of breath, rapid heart rate, and other symptoms of anemia. Low white blood cell count with promethazine intake can result in reduced immunity and increased risk for opportunistic infections.
- Low platelet cell production can result in episodes of easy bleeding and poor clotting. Patients can present with easy bruising and internal bleeding, with patients suffering blood loss in urine and stool, thus contributing to symptoms of anemia. Closely observe for any findings of easy bruising and frank blood in the urine and stool.
- Report any findings of anemia, flare-up of opportunistic infections, and episodes of blood in the urine and stool, following promethazine intake, to your physician immediately, for appropriate changes in the plan of care to be considered.
Integumentary side-effects
- Promethazine intake can increase the risk for skin rash and photosensitivity, in individuals exposed to sunlight. Individuals taking promethazine, especially those with history of photosensitivity, should avoid natural and bright lights or use sunscreens when getting out in the sun. Individuals taking promethazine also must avoid tanning centers, to prevent any photosensitive responses from developing.
- Promethazine also inhibits secretion of sweat, thus inhibiting the natural cooling mechanism of the body and can result in the body getting overheated. Individuals taking promethazine must avoid doing any physical exercise in warm environmental temperatures, to prevent risk for heat stroke. Observing compliance with fluid intake recommendations and dressing in light colored clothes, in warm environments, can help prevent hyperthermic body response.
