Patient/caregiver was educated on contraindications for using Metaxalone as follows:
- In the event of any current manifestations of any allergic response with this medication, report it to your physician or other health care personnel immediately, to check regarding your safety with continuing on intake of this medication.
- Metaxalone can interact with a lot of other medications, thus resulting in serious side-effects and toxicity. Concomitant administration of alcohol and drugs like OTC cough medications and antihistamines, other opioid medications like hydrocodone and codeine, other muscle relaxant medications, antidepressant medications, antipsychotics, and antianxiety medications, can also result in extreme depression of brain and respirations, thus potentiating the dizziness, confusion, and breathing difficulties caused by metaxalone and so, must be avoided taking along with metaxalone.
- Metaxalone must be avoided in individuals with history of severe head injury and brain damage. Individuals with history of head injury and brain damage, and severe respiratory disorders can be at a very high risk to present with severe depression of brain and associated respiratory and cardiovascular centers with metaxalone, respiratory center with metaxalone, leading to complications such as, coma, respiratory arrest, dangerous hypotension, and bradycardia, which can be fatal.
