Patient/caregiver was instructed upon therapeutic uses and mechanism of action of Remeron as follows:
- Neurotransmitters are chemicals that are manufactured in the brain and released by nerve endings, at the synapse, which is a junction between two nerves. This released neurotransmitter in the synapse communicates the impulse to the nerves around.
- A variety of neurotransmitters, such as, norepinephrine, serotonin, dopamine, and gamma-aminobutyric acid (GABA) play a significant role in regulating mood and behavior. The concentrations of these neurotransmitters must be closely balanced for regulation of mood and prevention of any mood disorders.
- Low levels of norepinephrine and serotonin is considered to be an important factor for symptoms of anxiety and depression.
- Remeron is an antidepressant medication, belonging to the class of atypical antidepressants, used to treat mood disorders, such as, major depression and anxiety.
- The mechanism of action of Remeron is not clearly known. It is believed that Remeron works by increasing the release of norepinephrine and serotonin, thus enhancing their activity in the brain. This helps with improved communication and appropriate desired nerve stimulation. This can contribute towards controlling symptoms of depression and promoting feelings of contentment and happiness.
- In addition to mood regulation, Remeron also helps to promote sleep and so, is used in individuals with insomnia and difficulty falling sleep. Remeron also promotes appetite and can be used in individuals with poor appetite, to help stimulate an increase in the intake.
