Patient/caregiver was educated on the side-effects of using Donepezil as follows:
Central nervous system side-effects
- Potentiation of acetylcholine action in the body, secondary to donepezil use, can result in disturbance in the neurotransmitter balance controlling the mood and behavior. This can result in increased risk of deterioration of mood disorders with worsening of clinical symptoms. Individuals can present with complaints such as, feeling low and depressed, anxiety, panic attacks, trouble sleeping, gross appetite changes, impulsiveness, agitation, aggression, and suicidal thoughts.
- Donepezil can induce some dizziness and confusion. Starting the medication at a low dose, watching closely for the therapeutic response, and gradually changing the dose, to help optimum control of your symptoms, can contribute to reducing the risk for drowsiness and dizziness due to the medication. Stay away from activities, such as, driving and operating heavy machinery, until you are used to the side effects caused by donepezil.
- Donepezil intake closer to the sleep time can result in insomnia, with patients presenting with restlessness, poor quality sleep, and irritability during the day time. If the insomnia is being severe, avoid taking the medication at bedtime.
