Patient/caregiver was educated on contraindications for using Gabitril as follows:

  1. Do not take Gabitril, if you ever manifested any allergic responses to intake of Gabitril or any other medications used to control seizures and nerve pain, such as, Lyrica and Cymbalta. In the event of an allergic response with any of these medications, check with your physician regarding your safety with intake of Gabitril.
  2. Gabitril use, especially in individuals with history of anxiety and bipolar disorder, carries risk of deterioration of mood disorders and worsening of clinical symptoms of mood disorders. Individuals can present with complaints such as, feeling low, anxiety, panic attacks, trouble sleeping, gross appetite changes, impulsiveness, agitation, aggression, and suicidal thoughts. So, Gabitril must be used with caution in such individuals, with periodical monitoring for symptoms of worsening mood and behavior.