Patient/caregiver was educated on contraindications for using Edluar as follows:
- When taken together, Edluar can interact with a number of other medications and can precipitate serious reactions. Some medications, such as, oral contraceptives, antibiotics, anti-GERD agents like omeprazole, inhibit the enzyme systems needed for the metabolism of Edluar. Concurrent administration of these medications with Edluar can prolong the duration of Edluar action, secondary to inhibition of Edluar metabolism, and result in toxicity. Avoid taking Edluar with grapefruit juice, as it can also inhibit the enzyme systems needed for the metabolism of Edluar and result in toxicity with Edluar.
- Individuals with history of breathing issues, such as, asthma sleep apnea, and COPD, must exercise extra precaution in watching out for any compromised breathing function, secondary to Edluar intake. Avoid taking Edluar along with any other products and drugs, which also carry the risk of depression of the respiratory center, such as, alcohol, OTC cough syrups, narcotic pain medications, antidepressants, and muscle relaxants. The individual influence of these medications on respirations can complement the effect of Edluar on respiration and lead to severe respiratory depression and can even be fatal.
