Patient/caregiver was instructed upon therapeutic uses of Pyridoxine as follows:

  1. Pyridoxine plays an important role in the synthesis of neurotransmitters, which are chemicals helping with conduction of nerve impulses from one nerve cell to another. These neurotransmitters in the brain and nervous system must be closely regulated and balanced, as they are essential in regulating mood and behavior. Deficiency of Pyridoxine can result in compromised synthesis of these neurotransmitters. Low levels of these chemicals in the brain contribute to symptoms of anxiety, depression, mania, and psychosis.
  2. New red blood cells are continually produced from the bone marrow, which replace the senile red blood cells in the circulation that are poorly functioning. Pyridoxine plays a significant role in synthesis of new red blood cells. Deficiency of Pyridoxine can result in impaired synthesis of new red blood cells, thus resulting in anemia.
  3. Pyridoxine acts as a co-factor for many enzymes involved in carbohydrate, fat, and protein metabolism. Deficiency of Pyridoxine thus results in compromised overall body metabolism, poor appetite, reduced energy production, malaise, weakness, and fatigue.
  4. Pyridoxine is needed for production of DNA in the various cells present in the different organs of the body. Thus, Pyridoxine plays an important role in cell multiplication, which helps to replace old and damaged cells with young and active cells, thus preserving the function. Deficiency of Pyridoxine can lead to compromised cell replication, whereby, replacement of old and damaged cells with active young cells will be compromised. This can result in compromised function of vital organs and early onset of symptoms of aging.
  5. Pyridoxine is also believed to be involved in detoxifying harmful metabolites produced in the body. Homocysteine is a toxic metabolite produced in the body from protein metabolism. Homocysteine produced in the body can be recycled and converted into useful proteins with the help of Pyridoxine. Deficiency of Pyridoxine compromises this conversion, thus leading to accumulation of high levels of homocysteine in the body. High homocysteine levels in the blood can be toxic and can contribute to elevated cholesterol, increased risk for heart attacks, strokes, and formation of blood clots. Elevated homocysteine levels in the blood can also result in early loss of bone, increasing risk for early onset of osteoporosis and fractures.
  6. Pyridoxine plays a significant role in the synthesis of melatonin, which is the hormone regulating sleep onset and wakefulness. Normal levels of melatonin in the body can also help with management and control of anxiety. Deficiency of Pyridoxine can affect synthesis of melatonin in the body, which can result in difficulty falling sleep, insomnia, and episodes of anxiety.
  7. Adequate levels of Pyridoxine are necessary during pregnancy to help normal fetal growth and development and prevent any development abnormalities in the newborn. Also, adequate levels of Pyridoxine during pregnancy can help with controlling the symptoms of morning sickness.
  8. Pyridoxine is an essential vitamin needed for the proper development and functioning of the brain and nerve cells. Deficiency of Pyridoxine can result in compromised development and maturity of nerve and brain cells, leading to conditions such as peripheral neuropathy, delayed thought processes, cognitive deficits, and dementia.